Combination of long-acting TRAIL and tumor cell-targeted photodynamic therapy as a novel strategy to overcome chemotherapeutic multidrug resistance and TRAIL resistance of colorectal cancer

Chemotherapeutic multidrug resistance (MDR) is the major hindrance for clinical therapy of colorectal cancer (CRC). Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) with selective cytotoxicity might overcome MDR of CRC cells. Unfortunately, cross-resistance to TRAIL has been detected...

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Vydáno v:Theranostics
Hlavní autoři: She, Tianshan, Shi, Qiuxiao, Li, Zhao, Feng, Yanru, Yang, Hao, Tao, Ze, Li, Heng, Chen, Jie, Wang, Shisheng, Liang, Yan, Cheng, Jingqiu, Lu, Xiaofeng
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2021
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7977453/
https://ncbi.nlm.nih.gov/pubmed/33754061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.51193
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