Polyamidoamine dendrimers-based nanomedicine for combination therapy with siRNA and chemotherapeutics to overcome multidrug resistance

Multidrug resistance (MDR) significantly decreases the therapeutic efficiency of anti-cancer drugs. Its reversal could serve as a potential method to restore the chemotherapeutic efficiency. Downregulation of MDR-related proteins with a small interfering RNA (siRNA) is a promising way to reverse the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Eur J Pharm Biopharm
Egile Nagusiak: Pan, Jiayi, Mendes, Livia Palmerston, Yao, Momei, Filipczak, Nina, Garai, Sumanta, Thakur, Ganesh A., Sarisozen, Can, Torchilin, Vladimir P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377860/
https://ncbi.nlm.nih.gov/pubmed/30633973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejpb.2019.01.006
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