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Combination of long-acting TRAIL and tumor cell-targeted photodynamic therapy as a novel strategy to overcome chemotherapeutic multidrug resistance and TRAIL resistance of colorectal cancer

Chemotherapeutic multidrug resistance (MDR) is the major hindrance for clinical therapy of colorectal cancer (CRC). Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) with selective cytotoxicity might overcome MDR of CRC cells. Unfortunately, cross-resistance to TRAIL has been detected...

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Publicat a:Theranostics
Autors principals: She, Tianshan, Shi, Qiuxiao, Li, Zhao, Feng, Yanru, Yang, Hao, Tao, Ze, Li, Heng, Chen, Jie, Wang, Shisheng, Liang, Yan, Cheng, Jingqiu, Lu, Xiaofeng
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7977453/
https://ncbi.nlm.nih.gov/pubmed/33754061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.51193
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