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Genetic variants in the regulatory T cell related pathway and colorectal cancer prognosis

BACKGROUND: High numbers of lymphocytes in tumor tissue, including T regulatory cells (Treg), have been associated with better colorectal cancer (CRC) survival. Tregs, a subset of CD4(+) T lymphocytes, are mediators of immunosuppression in cancer and therefore variants in genes related to Treg diffe...

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Detalhes bibliográficos
Publicado no:Cancer Epidemiol Biomarkers Prev
Main Authors: Neumeyer, Sonja, Hua, Xinwei, Seibold, Petra, Jansen, Lina, Benner, Axel, Burwinkel, Barbara, Halama, Niels, Berndt, Sonja I, Phipps, Amanda I., Sakoda, Lori C, Schoen, Robert E, Slattery, Martha L, Chan, Andrew T, Gala, Manish, Joshi, Amit D, Ogino, Shuji, Song, Mingyang, Herpel, Esther, Bläker, Hendrik, Kloor, Matthias, Scherer, Dominique, Ulrich, Alexis, Ulrich, Cornelia M, Win, Aung K, Figueiredo, Jane C, Hopper, John L., Macrae, Finlay, Milne, Roger L., Giles, Graham G., Buchanan, Daniel D, Peters, Ulrike, Hoffmeister, Michael, Brenner, Hermann, Newcomb, Polly A, Chang-Claude, Jenny
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7976673/
https://ncbi.nlm.nih.gov/pubmed/33008876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-20-0714
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