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A prognostic CpG score derived from epigenome-wide profiling of tumor tissue was independently associated with colorectal cancer survival

BACKGROUND: Results of previous studies on the association of the CpG island methylator phenotype (CIMP) with colorectal cancer (CRC) prognosis were inconsistent and mostly based on different CIMP definitions. The current study aimed to comprehensively investigate the associations between DNA methyl...

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Vydáno v:Clin Epigenetics
Hlavní autoři: Jia, Min, Zhang, Yan, Jansen, Lina, Walter, Viola, Edelmann, Dominic, Gündert, Melanie, Tagscherer, Katrin E., Roth, Wilfried, Bewerunge-Hudler, Melanie, Herpel, Esther, Kloor, Matthias, Ulrich, Alexis, Burwinkel, Barbara, Bläker, Hendrik, Chang-Claude, Jenny, Brenner, Hermann, Hoffmeister, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657180/
https://ncbi.nlm.nih.gov/pubmed/31340858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-019-0703-4
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