Genetic variants in the regulatory T cell related pathway and colorectal cancer prognosis

BACKGROUND: High numbers of lymphocytes in tumor tissue, including T regulatory cells (Treg), have been associated with better colorectal cancer (CRC) survival. Tregs, a subset of CD4(+) T lymphocytes, are mediators of immunosuppression in cancer and therefore variants in genes related to Treg diffe...

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Publicat a:Cancer Epidemiol Biomarkers Prev
Autors principals: Neumeyer, Sonja, Hua, Xinwei, Seibold, Petra, Jansen, Lina, Benner, Axel, Burwinkel, Barbara, Halama, Niels, Berndt, Sonja I, Phipps, Amanda I., Sakoda, Lori C, Schoen, Robert E, Slattery, Martha L, Chan, Andrew T, Gala, Manish, Joshi, Amit D, Ogino, Shuji, Song, Mingyang, Herpel, Esther, Bläker, Hendrik, Kloor, Matthias, Scherer, Dominique, Ulrich, Alexis, Ulrich, Cornelia M, Win, Aung K, Figueiredo, Jane C, Hopper, John L., Macrae, Finlay, Milne, Roger L., Giles, Graham G., Buchanan, Daniel D, Peters, Ulrike, Hoffmeister, Michael, Brenner, Hermann, Newcomb, Polly A, Chang-Claude, Jenny
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7976673/
https://ncbi.nlm.nih.gov/pubmed/33008876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-20-0714
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