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Structure and Mechanism of Pseudomonas aeruginosa PA0254/HudA, a prFMN-Dependent Pyrrole-2-carboxylic Acid Decarboxylase Linked to Virulence
[Image: see text] The UbiD family of reversible (de)carboxylases depends on the recently discovered prenylated-FMN (prFMN) cofactor for activity. The model enzyme ferulic acid decarboxylase (Fdc1) decarboxylates unsaturated aliphatic acids via a reversible 1,3-cycloaddition process. Protein engineer...
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| Gepubliceerd in: | ACS Catal |
|---|---|
| Hoofdauteurs: | , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American
Chemical Society
2021
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| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7976604/ https://ncbi.nlm.nih.gov/pubmed/33763291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.0c05042 |
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