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A phage-encoded anti-CRISPR enables complete evasion of type VI-A CRISPR-Cas immunity
The crRNA-guided nuclease Cas13 recognizes complementary viral transcripts to trigger the degradation of both host and viral RNA during the type VI CRISPR-Cas antiviral response. How viruses can counteract this immunity is not known. We describe a listeriophage (ϕLS46) encoding an anti-CRISPR protei...
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| Publicado no: | Science |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7975689/ https://ncbi.nlm.nih.gov/pubmed/32467331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abb6151 |
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