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Conditional tolerance of temperate phages via transcription-dependent CRISPR-Cas targeting
A fundamental feature of immune systems is the ability to distinguish pathogenic from self and commensal elements, and to attack the former but tolerate the latter(1). Prokaryotic CRISPR-Cas immune systems defend against phage infection using Cas nucleases and small RNA guides that specify one or mo...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4214910/ https://ncbi.nlm.nih.gov/pubmed/25174707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13637 |
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