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Backbone assignment of E. coli NfsB and the effects of addition of the cofactor analogue nicotinic acid

E. coli nitroreductase NfsB (also called NfnB) has been studied extensively, largely due to its potential for cancer gene therapy. A homodimeric flavoprotein of 216 residues, it catalyses the reduction of nitroaromatics to cytotoxic hydroxylamines by NADH and NADPH and also the reduction of quinones...

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Bibliografische gegevens
Gepubliceerd in:Biomol NMR Assign
Hoofdauteurs: Hyde, Eva I., Chau, Alex Ka-Wing, Smith, Lorna J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer Netherlands 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7974150/
https://ncbi.nlm.nih.gov/pubmed/33423170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12104-020-09997-w
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