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Backbone assignment of E. coli NfsB and the effects of addition of the cofactor analogue nicotinic acid

E. coli nitroreductase NfsB (also called NfnB) has been studied extensively, largely due to its potential for cancer gene therapy. A homodimeric flavoprotein of 216 residues, it catalyses the reduction of nitroaromatics to cytotoxic hydroxylamines by NADH and NADPH and also the reduction of quinones...

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Detalles Bibliográficos
Publicado en:Biomol NMR Assign
Main Authors: Hyde, Eva I., Chau, Alex Ka-Wing, Smith, Lorna J.
Formato: Artigo
Idioma:Inglês
Publicado: Springer Netherlands 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7974150/
https://ncbi.nlm.nih.gov/pubmed/33423170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12104-020-09997-w
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