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Backbone assignment of E. coli NfsB and the effects of addition of the cofactor analogue nicotinic acid

E. coli nitroreductase NfsB (also called NfnB) has been studied extensively, largely due to its potential for cancer gene therapy. A homodimeric flavoprotein of 216 residues, it catalyses the reduction of nitroaromatics to cytotoxic hydroxylamines by NADH and NADPH and also the reduction of quinones...

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Detalhes bibliográficos
Publicado no:Biomol NMR Assign
Main Authors: Hyde, Eva I., Chau, Alex Ka-Wing, Smith, Lorna J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7974150/
https://ncbi.nlm.nih.gov/pubmed/33423170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12104-020-09997-w
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