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Backbone NMR assignments of the C-terminal domain of the human prion protein and its disease‐associated T183A variant
Transmissible spongiform encephalopathies (TSEs) are fatal neurodegenerative disorders associated with the misfolding and aggregation of the human prion protein (huPrP). Despite efforts into investigating the process of huPrP aggregation, the mechanisms triggering its misfolding remain elusive. A nu...
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| Publicat a: | Biomol NMR Assign |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer Netherlands
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7974147/ https://ncbi.nlm.nih.gov/pubmed/33590433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12104-021-10005-y |
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