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Sparsely methylated mitochondrial cell free DNA released from cardiomyocytes contributes to systemic inflammatory response accompanied by atrial fibrillation

Systemic inflammation is assumed to be the consequence and the cause of atrial fibrillation (AF); however, the underlying mechanism remains unclear. We aimed to evaluate the level of cell-free DNA (cfDNA) in patients with AF and AF mimicking models, and to illuminate its impact on inflammation. Peri...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Yamazoe, Masahiro, Sasano, Tetsuo, Ihara, Kensuke, Takahashi, Kentaro, Nakamura, Wakana, Takahashi, Naomi, Komuro, Hiroaki, Hamada, Satomi, Furukawa, Tetsushi
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7973420/
https://ncbi.nlm.nih.gov/pubmed/33737532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-85204-7
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