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Piezo 1 activation facilitates cholangiocarcinoma metastasis via Hippo/YAP signaling axis

Tumor metastasis is one of the major factors for the high mortality in cholangiocarcinoma (CCA), but its underlying mechanisms are not fully understood. Here, we report that Piezo-type mechanosensitive ion channel component 1 (Piezo 1) is detected to be significantly upregulated in CCA tissues, whic...

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Vydáno v:Mol Ther Nucleic Acids
Hlavní autoři: Zhu, Biqiang, Qian, Wei, Han, Chaoqun, Bai, Tao, Hou, Xiaohua
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Gene & Cell Therapy 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7973248/
https://ncbi.nlm.nih.gov/pubmed/33767919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2021.02.026
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