Human Cytomegalovirus miR-US33as-5p Targets IFNAR1 to Achieve Immune Evasion During Both Lytic and Latent Infection

As the first line of antiviral defense, type I interferon (IFN) binds IFN receptor 1 (IFNAR1) and IFNAR2 to activate the Jak-STAT signal transduction pathway, producing IFN-stimulated genes (ISGs) to control viral infection. The mechanisms by which human cytomegalovirus (HCMV) counteracts the IFN pa...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Zhang, Qian, Song, Xin, Ma, Ping, Lv, Liping, Zhang, Yangyang, Deng, Jiang, Zhang, Yanyu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7973039/
https://ncbi.nlm.nih.gov/pubmed/33746965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.628364
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