Structural and Functional Dissection of the Human Cytomegalovirus Immune Evasion Protein US6

The human cytomegalovirus (HCMV) protein US6 inhibits the transporter associated with antigen processing (TAP). Since TAP transports antigenic peptides into the endoplasmic reticulum for binding to major histocompatibility class I molecules, inhibition of the transporter by HCMV US6 impairs the pres...

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Bibliographic Details
Main Authors: Dugan, Gillian E., Hewitt, Eric W.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268496/
https://ncbi.nlm.nih.gov/pubmed/18199642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01705-07
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