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The Efficacy of Antigen Processing Is Critical for Protection against Cytomegalovirus Disease in the Presence of Viral Immune Evasion Proteins

Cytomegaloviruses (CMVs) code for immunoevasins, glycoproteins that are specifically dedicated to interfere with the presentation of antigenic peptides to CD8 T cells. Nonetheless, the biological outcome is not an immune evasion of the virus, since CD8 T cells can control CMV infection even when imm...

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Bibliographic Details
Main Authors: Holtappels, Rafaela, Thomas, Doris, Reddehase, Matthias J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738254/
https://ncbi.nlm.nih.gov/pubmed/19553308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00936-09
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