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The Efficacy of Antigen Processing Is Critical for Protection against Cytomegalovirus Disease in the Presence of Viral Immune Evasion Proteins

Cytomegaloviruses (CMVs) code for immunoevasins, glycoproteins that are specifically dedicated to interfere with the presentation of antigenic peptides to CD8 T cells. Nonetheless, the biological outcome is not an immune evasion of the virus, since CD8 T cells can control CMV infection even when imm...

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Autores principales: Holtappels, Rafaela, Thomas, Doris, Reddehase, Matthias J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738254/
https://ncbi.nlm.nih.gov/pubmed/19553308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00936-09
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