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IFNAR1 Degradation: A New Mechanism for Tumor Immune Evasion?
Type I interferons have been shown to play a major role in anti-cancer immunity. In this issue, describe tumor-induced degradation of type I interferon receptor IFNAR1 chain as a new immune-evasion mechanism in colorectal cancers. Stabilizing IFNAR1 inhibits tumor growth and improves immunotherapy e...
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| Veröffentlicht in: | Cancer Cell |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7886182/ https://ncbi.nlm.nih.gov/pubmed/28196588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2017.01.012 |
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