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Dualmarker: a flexible toolset for exploratory analysis of combinatorial dual biomarkers for clinical efficacy

BACKGROUND: An increasing number of clinical trials require biomarker-driven patient stratification, especially for revolutionary immune checkpoint blockade therapy. Due to the complicated interaction between a tumor and its microenvironment, single biomarkers, such as PDL1 protein level, tumor muta...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Ma, Xiaopeng, Huang, Ruiqi, Wu, Xikun, Zhang, Pei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7972341/
https://ncbi.nlm.nih.gov/pubmed/33731020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-021-04050-6
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