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MutEnricher: a flexible toolset for somatic mutation enrichment analysis of tumor whole genomes

BACKGROUND: Analysis of somatic mutations from tumor whole exomes has fueled discovery of novel cancer driver genes. However, ~ 98% of the genome is non-coding and includes regulatory elements whose normal cellular functions can be disrupted by mutation. Whole genome sequencing (WGS), on the other h...

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Pubblicato in:BMC Bioinformatics
Autori principali: Soltis, Anthony R., Dalgard, Clifton L., Pollard, Harvey B., Wilkerson, Matthew D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7393734/
https://ncbi.nlm.nih.gov/pubmed/32736515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03695-z
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