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Proteomic identification of the UDP-GlcNAc: PI α1–6 GlcNAc-transferase subunits of the glycosylphosphatidylinositol biosynthetic pathway of Trypanosoma brucei

The first step of glycosylphosphatidylinositol (GPI) anchor biosynthesis in all eukaryotes is the addition of N-acetylglucosamine (GlcNAc) to phosphatidylinositol (PI) which is catalysed by a UDP-GlcNAc: PI α1–6 GlcNAc-transferase, also known as GPI GnT. This enzyme has been shown to be a complex of...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Ji, Zhe, Tinti, Michele, Ferguson, Michael A. J.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7971885/
https://ncbi.nlm.nih.gov/pubmed/33735232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0244699
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