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Anti-CD19 CAR T cells potently redirected to kill solid tumor cells

Successful CAR T cell therapy for the treatment of solid tumors requires exemplary CAR T cell expansion, persistence and fitness, and the ability to target tumor antigens safely. Here we address this constellation of critical attributes for successful cellular therapy by using integrated technologie...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Ambrose, Christine, Su, Lihe, Wu, Lan, Dufort, Fay J., Sanford, Thomas, Birt, Alyssa, Hackel, Benjamin J., Hombach, Andreas, Abken, Hinrich, Lobb, Roy R., Rennert, Paul D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7971483/
https://ncbi.nlm.nih.gov/pubmed/33735268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0247701
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