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Amiodarone Alters Cholesterol Biosynthesis through Tissue-Dependent Inhibition of Emopamil Binding Protein and Dehydrocholesterol Reductase 24

Amiodarone is prescribed for the treatment and prevention of irregular heartbeats. Although effective in clinical practice, the long-term use of amiodarone has many unwanted side effects, including cardiac, pulmonary, hepatic, and neurological toxicities. Our objective was to elucidate effects of am...

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Detalhes bibliográficos
Publicado no:ACS Chem Neurosci
Main Authors: Allen, Luke B., Genaro-Mattos, Thiago C., Anderson, Allison, Porter, Ned A., Mirnics, Károly, Korade, Zeljka
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7970401/
https://ncbi.nlm.nih.gov/pubmed/32286791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.0c00042
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