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Altered Cholesterol Biosynthesis Affects Drug Metabolism
[Image: see text] The last step of cholesterol biosynthesis is the conversion of 7-dehydrocholesterol (7-DHC) into cholesterol, a reaction catalyzed by dehydrocholesterol reductase 7 (DHCR7). Investigation of the effect of Dhcr7 single-allele mutations on the metabolism of aripiprazole (ARI) and car...
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| 出版年: | ACS Omega |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Chemical Society
2021
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| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7931400/ https://ncbi.nlm.nih.gov/pubmed/33681590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c05817 |
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