Oncogenic B-Myb Is Associated With Deregulation of the DREAM-Mediated Cell Cycle Gene Expression Program in High Grade Serous Ovarian Carcinoma Clinical Tumor Samples

Cell cycle control drives cancer progression and treatment response in high grade serous ovarian carcinoma (HGSOC). MYBL2 (encoding B-Myb), an oncogene with prognostic significance in several cancers, is highly expressed in most HGSOC cases; however, the clinical significance of B-Myb in this diseas...

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Veröffentlicht in:Front Oncol
Hauptverfasser: Iness, Audra N., Rubinsak, Lisa, Meas, Steven J., Chaoul, Jessica, Sayeed, Sadia, Pillappa, Raghavendra, Temkin, Sarah M., Dozmorov, Mikhail G., Litovchick, Larisa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Oncology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7969987/
https://ncbi.nlm.nih.gov/pubmed/33747961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.637193
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