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Pol α-primase dependent nuclear localization of the mammalian CST complex

The human CST complex composed of CTC1, STN1, and TEN1 is critically involved in telomere maintenance and homeostasis. Specifically, CST terminates telomere extension by inhibiting telomerase access to the telomeric overhang and facilitates lagging strand fill in by recruiting DNA Polymerase alpha p...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Commun Biol
Päätekijät: Kelich, Joseph M., Papaioannou, Harry, Skordalakes, Emmanuel
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7969954/
https://ncbi.nlm.nih.gov/pubmed/33731801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01845-4
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