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Pol α-primase dependent nuclear localization of the mammalian CST complex
The human CST complex composed of CTC1, STN1, and TEN1 is critically involved in telomere maintenance and homeostasis. Specifically, CST terminates telomere extension by inhibiting telomerase access to the telomeric overhang and facilitates lagging strand fill in by recruiting DNA Polymerase alpha p...
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| Publicado no: | Commun Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7969954/ https://ncbi.nlm.nih.gov/pubmed/33731801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01845-4 |
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