Comprehensive miRNome-Wide Profiling in a Neuronal Cell Model of Synucleinopathy Implies Involvement of Cell Cycle Genes

Growing evidence suggests that epigenetic mechanisms like microRNA-mediated transcriptional regulation contribute to the pathogenesis of parkinsonism. In order to study the influence of microRNAs (miRNAs), we analyzed the miRNome 2 days prior to major cell death in α-synuclein-overexpressing Lund hu...

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Détails bibliographiques
Publié dans:Front Cell Dev Biol
Auteurs principaux: Findeiss, Elisabeth, Schwarz, Sigrid C., Evsyukov, Valentin, Rösler, Thomas W., Höllerhage, Matthias, Chakroun, Tasnim, Nykänen, Niko-Petteri, Shen, Yimin, Wurst, Wolfgang, Kohl, Michael, Tost, Jörg, Höglinger, Günter U.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021
Sujets:
Cell and Developmental Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7969723/
https://ncbi.nlm.nih.gov/pubmed/33748099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.561086
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