Quercetin Antagonizes Glucose Fluctuation Induced Renal Injury by Inhibiting Aerobic Glycolysis via HIF-1α/miR-210/ISCU/FeS Pathway

Background and Objective: Glucose fluctuation (GF) has been reported to induce renal injury and diabetic nephropathy (DN). However, the mechanism still remains ambiguous. Mitochondrial energy metabolism, especially aerobic glycolysis, has been a hotspot of DN research for decades. The activation of...

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Bibliographische Detailangaben
Veröffentlicht in:Front Med (Lausanne)
Hauptverfasser: Xu, Wei-long, Liu, Su, Li, Nan, Ye, Li-fang, Zha, Min, Li, Chang-yin, Zhao, Yue, Pu, Qiang, Bao, Jin-jing, Chen, Xing-jie, Yu, Jiang-yi, Pei, Ying-hao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Medicine
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7969708/
https://ncbi.nlm.nih.gov/pubmed/33748166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2021.656086
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