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Klotho negatively regulated aerobic glycolysis in colorectal cancer via ERK/HIF1α axis
BACKGROUND: Klotho (KL) was originally characterized as an aging suppressor gene, and has been identified as a tumor suppressor gene in a variety of cancers, including colorectal cancer. Recent years have witnessed the importance of metabolism transformation in cancer cell malignancies maintenance....
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| Publicado en: | Cell Commun Signal |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5994118/ https://ncbi.nlm.nih.gov/pubmed/29884183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-018-0241-2 |
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