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Simultaneous Ablation of the Catalytic AMPK α-Subunit SNF1 and Mitochondrial Matrix Protease CLPP Results in Pronounced Lifespan Extension

Organismic aging is known to be controlled by genetic and environmental traits. Pathways involved in the control of cellular metabolism play a crucial role. Previously, we identified a role of PaCLPP, a mitochondrial matrix protease, in the control of the mitochondrial energy metabolism, aging, and...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Heinz, Daniela, Krotova, Evgeniia, Hamann, Andrea, Osiewacz, Heinz D.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7969656/
https://ncbi.nlm.nih.gov/pubmed/33748105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.616520
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