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Targeting the autophagy promoted antitumor effect of T-DM1 on HER2-positive gastric cancer
Trastuzumab emtansine (T-DM1), an antibody-drug conjugate consisted of the HER2-targeted monoclonal antibody trastuzumab and the tubulin inhibitor emtansine, has shown potent therapeutic value in HER2-positive breast cancer (BC). However, a clinical trial indicated that T-DM1 exerts a limited effect...
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| Publié dans: | Cell Death Dis |
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| Auteurs principaux: | , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7969610/ https://ncbi.nlm.nih.gov/pubmed/33731670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03349-1 |
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