SAMHD1 restrains aberrant nucleotide insertions at repair junctions generated by DNA end joining

Aberrant end joining of DNA double strand breaks leads to chromosomal rearrangements and to insertion of nuclear or mitochondrial DNA into breakpoints, which is commonly observed in cancer cells and constitutes a major threat to genome integrity. However, the mechanisms that are causative for these...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Akimova, Ekaterina, Gassner, Franz Josef, Schubert, Maria, Rebhandl, Stefan, Arzt, Claudia, Rauscher, Stefanie, Tober, Vanessa, Zaborsky, Nadja, Greil, Richard, Geisberger, Roland
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2021
Fag:
Genome Integrity, Repair and Replication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7969033/
https://ncbi.nlm.nih.gov/pubmed/33591315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab051
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker