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Dynamics of Ku and bacterial non-homologous end-joining characterized using single DNA molecule analysis
We use single-molecule techniques to characterize the dynamics of prokaryotic DNA repair by non-homologous end-joining (NHEJ), a system comprised only of the dimeric Ku and Ligase D (LigD). The Ku homodimer alone forms a ∼2 s synapsis between blunt DNA ends that is increased to ∼18 s upon addition o...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7969030/ https://ncbi.nlm.nih.gov/pubmed/33590005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab083 |
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