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Interplay of folded domains and the disordered low-complexity domain in mediating hnRNPA1 phase separation
Liquid–liquid phase separation underlies the membrane-less compartmentalization of cells. Intrinsically disordered low-complexity domains (LCDs) often mediate phase separation, but how their phase behavior is modulated by folded domains is incompletely understood. Here, we interrogate the interplay...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7969017/ https://ncbi.nlm.nih.gov/pubmed/33577679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab063 |
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