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Smart-ORF: a single-molecule method for accessing ribosome dynamics in both upstream and main open reading frames
Upstream open reading frame (uORF) translation disrupts scanning 43S flux on mRNA and modulates main open reading frame (mORF) translation efficiency. Current tools, however, have limited access to ribosome dynamics in both upstream and main ORFs of an mRNA. Here, we develop a new two-color in vitro...
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| Udgivet i: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7969011/ https://ncbi.nlm.nih.gov/pubmed/33330921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1185 |
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