27-Hydroxycholesterol Alters Synaptic Structural and Functional Plasticity in Hippocampal Neuronal Cultures

This study aimed to explore the neurotoxic effects of 27-hydroxycholesterol (27-OHC), a major circulating cholesterol active derivative in brain on synaptic structural and functional plasticity in primary hippocampal neurons. Newborn SD rat primary hippocampal neurons were treated with 0, 1, 3, 10,...

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Detalhes bibliográficos
Publicado no:J Neuropathol Exp Neurol
Main Authors: Wang, Yushan, An, Yu, Zhang, Dandi, Yu, Huiyan, Zhang, Xiaona, Wang, Ying, Tao, Lingwei, Xiao, Rong
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7967841/
https://ncbi.nlm.nih.gov/pubmed/30753597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nlz002
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