Phospho-valproic acid (MDC-1112) suppresses glioblastoma growth in preclinical models through the inhibition of STAT3 phosphorylation

New therapeutic strategies against glioblastoma multiforme (GBM) are urgently needed. Signal transducer and activator of transcription 3 (STAT3), constitutively active in many GBM tumors, plays a major role in GBM tumor growth and represents a potential therapeutic target. We have documented previou...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Carcinogenesis
Autori principali: Luo, Dingyuan, Fraga-Lauhirat, Magdalena, Millings, Jonathan, Ho, Cristella, Villarreal, Emily M, Fletchinger, Teresa C, Bonfiglio, James V, Mata, Leyda, Nemesure, Matthew D, Bartels, Lauren E, Wang, Ruixue, Rigas, Basil, Mackenzie, Gerardo G
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
Soggetti:
Carcinogenesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7967702/
https://ncbi.nlm.nih.gov/pubmed/30994173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgz069
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi