Cytosolic Delivery of Thiolated Neoantigen Nano‐Vaccine Combined with Immune Checkpoint Blockade to Boost Anti‐Cancer T Cell Immunity

Although tumor‐specific neoantigen‐based cancer vaccines hold tremendous potential, it still faces low cross‐presentation associated with severe degradation via endocytosis pathway. Herein, a thiolated nano‐vaccine allowing direct cytosolic delivery of neoantigen and Toll like receptor 9 agonist CpG...

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Detalhes bibliográficos
Publicado no:Adv Sci (Weinh)
Main Authors: Zhang, Da, Lin, Ziguo, Wu, Ming, Cai, Zhixiong, Zheng, Youshi, He, Lei, Li, Zhenli, Zhou, Jie, Sun, Liqin, Chen, Geng, Zeng, Yongyi, Li, Juan, Liu, Jingfeng, Yang, Huanghao, Liu, Xiaolong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
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Full Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7967047/
https://ncbi.nlm.nih.gov/pubmed/33747739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.202003504
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