Converting Immune Cold into Hot by Biosynthetic Functional Vesicles to Boost Systematic Antitumor Immunity

Summary: Immune cold tumor characterized by low immunogenicity, insufficient and exhausted tumor-infiltrating lymphocytes, and immunosuppressive microenvironment is the main bottleneck responsible for low patient response rate of immune checkpoint blockade. Here, we developed biosynthetic functional...

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Detalhes bibliográficos
Main Authors: Ming Wu, Dongye Zheng, Da Zhang, Peiwen Yu, Lianli Peng, Feng Chen, Ziguo Lin, Zhixiong Cai, Jiong Li, Zuwu Wei, Xinyi Lin, Jingfeng Liu, Xiaolong Liu
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020-07-01
Colecção:iScience
Assuntos:
Immunity
Immune Response
Cell Biology
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2589004220305289
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