Remodeling Tumor‐Associated Neutrophils to Enhance Dendritic Cell‐Based HCC Neoantigen Nano‐Vaccine Efficiency

Abstract Hepatocellular carcinoma (HCC) commonly emerges in an immunologically “cold” state, thereafter protects it away from cytolytic attack by tumor‐infiltrating lymphocytes, resulting in poor response to immunotherapy. Herein, an acidic/photo‐sensitive dendritic cell (DCs)‐based neoantigen nano‐...

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Detalhes bibliográficos
Main Authors: Yunhao Wang, Qingfu Zhao, Binyu Zhao, Youshi Zheng, Qiuyu Zhuang, Naishun Liao, Peiyuan Wang, Zhixiong Cai, Da Zhang, Yongyi Zeng, Xiaolong Liu
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2022-04-01
Colecção:Advanced Science
Assuntos:
dendritic cell‐based vaccine
immunotherapy
neoantigen
neutrophils
photodynamic therapy
Acesso em linha:https://doi.org/10.1002/advs.202105631
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