Antioxidant preconditioning improves therapeutic outcomes of adipose tissue-derived mesenchymal stem cells through enhancing intrahepatic engraftment efficiency in a mouse liver fibrosis model

Abstract Background Although it has been preclinically suggested that adipose tissue-derived mesenchymal stem cell (ADSC)-based therapy could effectively treat chronic liver diseases, the hepatic engraftment of ADSCs is still extremely low, which severely limits their long-term efficacy for chronic...

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Detalhes bibliográficos
Main Authors: Naishun Liao, Yingjun Shi, Yingchao Wang, Fangyu Liao, Bixing Zhao, Youshi Zheng, Yongyi Zeng, Xiaolong Liu, Jingfeng Liu
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2020-06-01
Colecção:Stem Cell Research & Therapy
Assuntos:
Adipose tissue-derived mesenchymal stem cells
Reactive oxygen species
Liver fibrosis
Cell engraftment efficiency
Stem cell therapy
Acesso em linha:http://link.springer.com/article/10.1186/s13287-020-01763-y
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