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Lacto-N-biose synthesis via a modular enzymatic cascade with ATP regeneration

Human milk oligosaccharides (HMOs), the third most abundant solid component of human milk, are reported to be beneficial to infant health. The biosynthesis of lacto-N-biose (LNB), the building block for HMOs, suffers from excessive addition of cofactors and intermediate inhibition. Here, we develope...

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Podrobná bibliografie
Vydáno v:iScience
Hlavní autoři: Du, Zhiqiang, Liu, Zhengyao, Tan, Yinshuang, Niu, Kangle, Guo, Wei, Jia, Yangyang, Fang, Xu
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7967015/
https://ncbi.nlm.nih.gov/pubmed/33748718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102236
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