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Modular Enzymatic Cascade Synthesis of Vitamin B(5) and Its Derivatives
Access to vitamin B(5) [(R)‐pantothenic acid] and both diastereoisomers of α‐methyl‐substituted vitamin B(5) [(R)‐ and (S)‐3‐((R)‐2,4‐dihydroxy‐3,3‐dimethylbutanamido)‐2‐methylpropanoic acid] was achieved using a modular three‐step biocatalytic cascade involving 3‐methylaspartate ammonia lyase (MAL)...
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| Gepubliceerd in: | Chemistry |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
John Wiley and Sons Inc.
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6471175/ https://ncbi.nlm.nih.gov/pubmed/30192043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201804151 |
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