Engineered C–N Lyase: Enantioselective Synthesis of Chiral Synthons for Artificial Dipeptide Sweeteners

Aspartic acid derivatives with branched N‐alkyl or N‐arylalkyl substituents are valuable precursors to artificial dipeptide sweeteners such as neotame and advantame. The development of a biocatalyst to synthesize these compounds in a single asymmetric step is an as yet unmet challenge. Reported here...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Angew Chem Int Ed Engl
Hlavní autoři: Zhang, Jielin, Grandi, Eleonora, Fu, Haigen, Saravanan, Thangavelu, Bothof, Laura, Tepper, Pieter G., Thunnissen, Andy‐Mark W. H., Poelarends, Gerrit J.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6973171/
https://ncbi.nlm.nih.gov/pubmed/31625664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201910704
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky