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Lacto-N-biose synthesis via a modular enzymatic cascade with ATP regeneration

Human milk oligosaccharides (HMOs), the third most abundant solid component of human milk, are reported to be beneficial to infant health. The biosynthesis of lacto-N-biose (LNB), the building block for HMOs, suffers from excessive addition of cofactors and intermediate inhibition. Here, we develope...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Du, Zhiqiang, Liu, Zhengyao, Tan, Yinshuang, Niu, Kangle, Guo, Wei, Jia, Yangyang, Fang, Xu
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7967015/
https://ncbi.nlm.nih.gov/pubmed/33748718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102236
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