Insights into the catalytic properties of the mitochondrial rhomboid protease PARL

The rhomboid protease PARL is a critical regulator of mitochondrial homeostasis through its cleavage of substrates such as PINK1, PGAM5, and Smac/Diablo, which have crucial roles in mitochondrial quality control and apoptosis. However, the catalytic properties of PARL, including the effect of lipids...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Lysyk, Laine, Brassard, Raelynn, Arutyunova, Elena, Siebert, Verena, Jiang, Zhenze, Takyi, Emmanuella, Morrison, Melissa, Young, Howard S., Lemberg, Marius K., O’Donoghue, Anthony J., Lemieux, M. Joanne
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2021
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7966987/
https://ncbi.nlm.nih.gov/pubmed/33556373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100383
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