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The PARL family of mitochondrial rhomboid proteases

Rhomboids are an ancient and conserved family of intramembrane-cleaving proteases, a small group of proteolytic enzymes capable of hydrolyzing a peptide bond within a transmembrane helix that anchors a substrate protein to the membrane. Mitochondrial rhomboids evolved in eukaryotes to coordinate a c...

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Bibliographic Details
Main Authors: Hill, R. Blake, Pellegrini, Luca
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908206/
https://ncbi.nlm.nih.gov/pubmed/20045481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2009.12.011
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