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Lgals9 deficiency ameliorates obesity by modulating redox state of PRDX2

The adipose tissue is regarded as an endocrine organ and secretes bioactive adipokines modulating chronic inflammation and oxidative stress in obesity. Gal-9 is secreted out upon cell injuries, interacts with T-cell immunoglobulin-3 (Tim-3) and induces apoptosis in activated Th1 cells. Gal-9 also bi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nunoue, Tomokazu, Yamaguchi, Satoshi, Teshigawara, Sanae, Katayama, Akihiro, Nakatsuka, Atsuko, Eguchi, Jun, Niki, Toshiro, Wada, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7966757/
https://ncbi.nlm.nih.gov/pubmed/33727589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-85080-1
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